(Marie Skłodowska-Curie Actions MSCA) Understanding role of neuroactive compounds in the diet in the development of neurodegenerative diseases.

Growing evidence points to the links between diet, gut, and neurodegenerative diseases (ND). Funded by the Marie Skłodowska-Curie Actions programme, the NeuroTOm project aims to understand the significance of exposure to neuroactive compounds in the diet. Using tomato as a food source, the study will elucidate the role of these chemicals in the gut-brain axis and the ND disease development after digestion. The neuroprotective and neurodisrupting compounds from organic, conventional, and processed tomatoes will be characterised by mass spectrometry. In vitro colon models will be employed to study the fate of these compounds in the gut and identify gut-microbial metabolites and their effect on intestinal epithelium cells.

PNRR Mission 4: Education and Research, Component 2: From Research to Enterprise, Investment 1.3 - Partnerships extended to universities, research centres, enterprises and research project funding:

• MUR Notice No. 341 of 15 March 2022 
• Financing € 114,500,000.00 
• Directorial Decree granting MUR No. 1550 of 11 October 2022 
• Identification Code: PE0000003 
• CUP B43C22000770006